When my hand cramped up while doing some artwork on the computer, the boy suggested I look into replacing my mouse. I did some research and in the end, I bought a Wacom Intuos.
There is definitely a learning curve since the stylus requires more hand movement than the mouse does. And I found it works much better in front of me, angled ... just like you would draw on paper.
I still use my mouse for every other application but this Wacom stylus is amazing for Photoshop. Here's my first official test drawing which took me about 10 minutes.
The mere thought of attempting this with a mouse gives me carpal tunnel.